Next-generation sequencing (NGS) target enrichment enables you to focus on your regions of interest in the human genome, hence greatly improving sample capacity and enabling faster results. Compared to other hybridization-based enrichment tech-nologies on the market, Roche products provide the highest capture efficiency and coverage uniformity available 1,2 as a result of its superior design algorithms and pro-prietary probe synthesis technology.
Roche sequence capture products have en-abled effective enrichment of a wide variety of genome regions from a broad range of sample types for high- fidelity detection of SNVs (single nucleotide variations), CNVs (copy number variations), indels (insertions and deletions), translocations, epigenomic events, RNA transcription and more.
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SeqCap Target Enrichment Systems is a solution-based capture method that enables enrichment of the whole exome or customer regions of interest in a single test tube with up to 2.1 million overlapping probes.
Flexible and Fast workflow
New HyperCap workflow combines Kapa Hyper Libraries with optimized SeqCap EZ protocol to yield an automation friendly workflow with superior performance across multiple sample types and starting amounts, optional Kapa Hyper Plus enzymatic frag-mentation offers further workflow streamlin-ing and removes capital equipment needs.
1 Clark, M., et al. (2011).Nat. Biotech.; doi:10.1038/nbt.1975.
2 Bodi, K., et al. (2013). J Biomol Tech. Jul;24(2):73-86. doi: 10.7171/jbt.13-2402-002.